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Protein Folding Protocols by Yawen Bai (English) Paperback Book

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eBay-objectnummer:386717575621
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Specificaties

Objectstaat
Nieuw: Een nieuw, ongelezen en ongebruikt boek in perfecte staat waarin geen bladzijden ontbreken of ...
ISBN-13
9781617376764
Book Title
Protein Folding Protocols
ISBN
9781617376764
Subject Area
Science
Publication Name
Protein Folding Protocols
Item Length
9 in
Publisher
Humana Press
Subject
Life Sciences / Cell Biology, Life Sciences / Biochemistry
Publication Year
2010
Series
Methods in Molecular Biology Ser.
Type
Textbook
Format
Trade Paperback
Language
English
Author
Yawen Bai
Item Width
6 in
Item Weight
17.9 Oz
Number of Pages
Xiv, 328 Pages

Over dit product

Product Information

Protein Folding Protocols presents protocols for studying and characterizing steps and conformational ensembles populating pathways in protein folding from the unfolded to the folded state. It further presents a sample of approaches toward the prediction of protein structure starting from the amino acid sequence, in the absence of overall homologous sequences. Protein folding is a crucial step in the transfer of genetic information from the DNA to the protein. The Genome Project has led to a huge number of available DNA sequences and, therefore, protein sequences. The Structural Genomics initiative largely aims to obtain "new" folds not currently present in the Protein Data Bank. Yet, the number of available structures inevitably lags behind the number of sequences. At the same time, an equally important problem is to find out the types and scope of dissimilar (nonhomologous) protein sequences that adopt a similar fold. Assembling data and comprehension of the sequence space of protein folds should be very useful in computational protein structure prediction. This would enhance the scope of homology modeling, which currently is the method of choice. Thus, experimental and theoretical studies on the relationship between sequence and structure are critical. Figuring out the relationship between sequence and structure would further assist in the prediction of fibril structures observed in protein misfolding diseases, and in figuring out the conformational changes and dynamics resulting from mutations. Protein folding is one of the most important and challenging problems in current molecular and chemical biology.

Product Identifiers

Publisher
Humana Press
ISBN-10
1617376760
ISBN-13
9781617376764
eBay Product ID (ePID)
109338277

Product Key Features

Author
Yawen Bai
Publication Name
Protein Folding Protocols
Format
Trade Paperback
Language
English
Subject
Life Sciences / Cell Biology, Life Sciences / Biochemistry
Publication Year
2010
Series
Methods in Molecular Biology Ser.
Type
Textbook
Subject Area
Science
Number of Pages
Xiv, 328 Pages

Dimensions

Item Length
9 in
Item Width
6 in
Item Weight
17.9 Oz

Additional Product Features

Intended Audience
Scholarly & Professional
Series Volume Number
350
Number of Volumes
1 Vol.
Lc Classification Number
Qh573-671
Reviews
"...great value to graduate students and researchers who would like to learn about modern techniques to probe protein folding events." -Journal of American Chemical Society
Table of Content
Infrared Temperature-Jump Study of the Folding Dynamics of ?-Helices and ?-Hairpins.- The Use of High-Pressure Nuclear Magnetic Resonance to Study Protein Folding.- Characterization of Denatured Proteins Using Residual Dipolar Couplings.- Characterizing Residual Structure in Disordered Protein States Using Nuclear Magnetic Resonance.- Population and Structure Determination of Hidden Folding Intermediates by Native-State Hydrogen Exchange-Directed Protein Engineering and Nuclear Magnetic Resonance.- Characterizing Protein Folding Transition States Using ?-Analysis.- Advances in the Analysis of Conformational Transitions in Peptides Using Differential Scanning Calorimetry.- Application of Single Molecule Förster Resonance Energy Transfer to Protein Folding.- Single Molecule Studies of Protein Folding Using Atomic Force Microscopy.- Using Triplet-Triplet Energy Transfer to Measure Conformational Dynamics in Polypeptide Chains.- A Hierarchical Protein Folding Scheme Based on the Building Block Folding Model.- Replica Exchange Molecular Dynamics Method for Protein Folding Simulation.- Estimation of Folding Probabilities and ? Values From Molecular Dynamics Simulations of Reversible Peptide Folding.- Packing Regularities in Biological Structures Relate to Their Dynamics.- Intermediates and Transition States in Protein Folding.- Thinking the Impossible.
Copyright Date
2006
Dewey Decimal
572/.633
Dewey Edition
22
Illustrated
Yes

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