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Dopamine Transporters : Chemistry, Biology, and Pharmacology, Hardcover by Tr...
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Specificaties
- Objectstaat
- Book Title
- Dopamine Transporters : Chemistry, Biology, and Pharmacology
- ISBN
- 9780470117903
- Subject Area
- Science, Medical
- Publication Name
- Dopamine Transporters : Chemistry, Biology, and Pharmacology
- Publisher
- Wiley & Sons, Incorporated, John
- Item Length
- 9.4 in
- Subject
- Neuroscience, Biochemistry, Chemistry / Industrial & Technical
- Publication Year
- 2008
- Series
- Wiley Series in Drug Discovery and Development Ser.
- Type
- Textbook
- Format
- Hardcover
- Language
- English
- Item Height
- 1.1 in
- Item Weight
- 27.3 Oz
- Item Width
- 6.2 in
- Number of Pages
- 464 Pages
Over dit product
Product Identifiers
Publisher
Wiley & Sons, Incorporated, John
ISBN-10
0470117907
ISBN-13
9780470117903
eBay Product ID (ePID)
64434735
Product Key Features
Number of Pages
464 Pages
Language
English
Publication Name
Dopamine Transporters : Chemistry, Biology, and Pharmacology
Publication Year
2008
Subject
Neuroscience, Biochemistry, Chemistry / Industrial & Technical
Type
Textbook
Subject Area
Science, Medical
Series
Wiley Series in Drug Discovery and Development Ser.
Format
Hardcover
Dimensions
Item Height
1.1 in
Item Weight
27.3 Oz
Item Length
9.4 in
Item Width
6.2 in
Additional Product Features
Intended Audience
Scholarly & Professional
LCCN
2007-046853
Reviews
"Much of what will be accomplished in the coming years will require an understanding of the issues and tools presented here. No doubt, those focused on other synaptic transporters will be jealous of this resource and should demand companion volumes." ( The Quarterly Review of Biology , March 2010) "The book is well written and the chapters are well illustrated where appropriate. It is a valuable addition to the bookshelf of anyone interested in dopaminergic neurotransmission." ( Journal of Medicinal Chemistry , March 2009)
Dewey Edition
22
Series Volume Number
7
Illustrated
Yes
Dewey Decimal
612.8/042
Table Of Content
Contributors. Preface. Part I: Biochemistry and Molecular Biology. Chapter 1: The Dopamine Transporter: An Anatomical Perspective (Hilary R. Smith, Thomas J. Beveridge, Colleen A. Hanlon, Linda J. Porrino). Chapter 2: Dopamine Transporter, Disease States and Pathology (Deborah C. Mash). Chapter 3: Cloning and Genetic Analysis of Dopamine Transporters (David J. Vandenbergh). Chapter 4: Molecular Structure and Composition of Dopamine Transporters (M. Laura Parnas and Roxanne A. Vaughan). Chapter 5: Electrochemical Characterization of Dopamine Transporters (Evgeny A. Budygin and Sara R. Jones). Part II: Medicinal Chemistry. Chapter 6: Tropane-Based Dopamine Transporter-uptake Inhibitors (Scott P. Runyon and F. Ivy Carroll). Chapter 7: The Benztropines: Atypical Dopamine-Uptake Inhibitors that Provide Clues About Cocaine's Mechanism at the Dopamine Transporter (Amy Hauck Newman and Jonathan L. Katz). Chapter 8. Structure-Activity Relationship of GBR 12909 Ligands (Thomas E. Prisinzano and Kenner C. Rice). Chapter 9: Structure-Activity Relationship Study of Piperidine Derivatives for Dopamine Transporters (Prashant S. Kharkar, Maarten E. A. Reith, and Aloke K. Dutta). Chapter 10: Non-Nitrogen-Containing Dopamine Transporter-Uptake Inhibitors (Peter C. Meltzer). Chapter 11: Dopamine-Releasing Agents (Bruce E. Blough). Part III: Pharmacology. Chapter 12: PET/SPECT Imaging Studies of the Plasma Membrane Dopamine Transporter. (Paul Cumming, Weiguo Ye, Dean F. Wong). Chapter 13: In Vitro Studies of Dopamine Transporter Function and Regulation (Brian R. Hoover, Bruce H. Mandt and Nancy R. Zahniser). Chapter 14: In Vivo Studies of Dopamine Transporter Function (Jane B. Acri). Index.
Synopsis
Both a reference source for researchers and a text for graduate students investigating the various aspects of the dopamine transporter (DAT), Dopamine Transporter: Chemistry, Biology, and Pharmacology includes aspects of chemistry, biology, and pharmacology and provides a strong general overview of this neurotransmitter., Understanding the dopamine transporter can lead to new therapies for neurological disorders This book consolidates current information on the dopamine transporter (DAT) in relationto medicinal chemistry and synthesis, biology and pathology, and pharmacology. Because of DAT's role in diseases such as Parkinson's, schizophrenia, attention deficit hyperactivity disorder (ADHD), Tourette syndrome, and drug abuse (in particular, cocaine addiction), DAT research is an exploding field. Tremendous advances have been made toward understanding how it impacts a variety of neurological disease states and disorders. This reference provides a broad overview of current knowledge that is detailed enough to furnish a basic understanding of the biological, chemical, and pharmacological aspects of DAT in one comprehensive reference. With contributions from eminent scientists who are experts in their particular areas, Dopamine Transporters: Chemistry, Biology, and Pharmacology Reviews current studies and research in the areas of DAT function, pathological conditions, cloning, molecular structure, and electrochemical characterization Covers findings in the medicinal chemistry of DAT-inhibitory ligands and substrates, discussing the chemical syntheses and summarizing the various structure-activity relationships of important classes of dopamine uptake inhibitors and dopamine releasers Has chapters that focus on technologies for future DAT study, including imaging and in vivo and in vitro methods This is a hands-on reference for researchers, medicinal chemists, pharmacologists, and biologists working with DAT or related proteins and for students in related areas of study., Understanding the dopamine transporter can lead to new therapies for neurological disorders This book consolidates current information on the dopamine transporter (DAT) in relationto medicinal chemistry and synthesis, biology and pathology, and pharmacology. Because of DAT's role in diseases such as Parkinson's, schizophrenia, attention deficit hyperactivity disorder (ADHD), Tourette syndrome, and drug abuse (in particular, cocaine addiction), DAT research is an exploding field. Tremendous advances have been made toward understanding how it impacts a variety of neurological disease states and disorders. This reference provides a broad overview of current knowledge that is detailed enough to furnish a basic understanding of the biological, chemical, and pharmacological aspects of DAT in one comprehensive reference. With contributions from eminent scientists who are experts in their particular areas, Dopamine Transporters: Chemistry, Biology, and Pharmacology: Reviews current studies and research in the areas of DAT function, pathological conditions, cloning, molecular structure, and electrochemical characterization Covers findings in the medicinal chemistry of DAT-inhibitory ligands and substrates, discussing the chemical syntheses and summarizing the various structure-activity relationships of important classes of dopamine uptake inhibitors and dopamine releasers Has chapters that focus on technologies for future DAT study, including imaging and in vivo and in vitro methods This is a hands-on reference for researchers, medicinal chemists, pharmacologists, and biologists working with DAT or related proteins and for students in related areas of study., Understanding the dopamine transporter can lead to new therapies for neurological disorders This book consolidates current information on the dopamine transporter (DAT) in relationto medicinal chemistry and synthesis, biology and pathology, and pharmacology. Because of DAT's role in diseases such as Parkinson's, schizophrenia, attention deficit hyperactivity disorder (ADHD), Tourette syndrome, and drug abuse (in particular, cocaine addiction), DAT research is an exploding field. Tremendous advances have been made toward understanding how it impacts a variety of neurological disease states and disorders. This reference provides a broad overview of current knowledge that is detailed enough to furnish a basic understanding of the biological, chemical, and pharmacological aspects of DAT in one comprehensive reference. With contributions from eminent scientists who are experts in their particular areas, Dopamine Transporters: Chemistry, Biology, and Pharmacology : Reviews current studies and research in the areas of DAT function, pathological conditions, cloning, molecular structure, and electrochemical characterization Covers findings in the medicinal chemistry of DAT-inhibitory ligands and substrates, discussing the chemical syntheses and summarizing the various structure-activity relationships of important classes of dopamine uptake inhibitors and dopamine releasers Has chapters that focus on technologies for future DAT study, including imaging and in vivo and in vitro methods This is a hands-on reference for researchers, medicinal chemists, pharmacologists, and biologists working with DAT or related proteins and for students in related areas of study.
LC Classification Number
QP563.D66D667 2008
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