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Diabetic Cardiomyopathy: Echocardiographic and Clinical Characteristics by Slavi

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eBay-objectnummer:364658324383
Laatst bijgewerkt op 19 mrt 2024 07:47:54 CETAlle herzieningen bekijkenAlle herzieningen bekijken

Specificaties

Objectstaat
Nieuw: Een nieuw, ongelezen en ongebruikt boek in perfecte staat waarin geen bladzijden ontbreken of ...
ISBN-13
9781536169577
Book Title
Diabetic Cardiomyopathy
ISBN
9781536169577
Publication Year
2020
Type
Textbook
Format
Hardcover
Language
English
Publication Name
Diabetic Cardiomyopathy: Echocardiographic and Clinical Characteristics
Author
Slavica Mitrovska
Publisher
NOVA Science Publishers INC International Concepts
Subject
Medicine
Item Weight
546g
Number of Pages
282 Pages

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Product Information

Background: Diabetic cardiomyopathy is defined as heart failure independent of the coronary artery, valve disease and hypertension. It has multifactorial aetiology but the pathogenesis is incompletely understood. Hyperglycemia, hyperlipidemia and inflammation with high oxidative stress lead to structural and functional alterations of the left ventricle (LV) and promote diabetic cardiomyopathy. Diastolic dysfunction is an early sign of diabetic cardiomyopathy. It has a long asymptomatic period, but with time leads to loss of contractile function. Hence, the identification of subclinical diabetic cardiomyopathy and correction of potentially modified risk factors are very important to delay the onset of heart failure. The aim: We aimed to assess the LV function in asymptomatic diabetic patients and its correlation with clinical and biochemical parameters. Study design: Cross-sectional study that includes a total number of 137 subjects. The target group consists of 72 asymptomatic normotensive patients with diabetes mellitus type 2, without coronary artery and valve disease. The control group is composed of 65 healthy subjects. Methods: All patients were subject to echocardiography (conventional 2D, M-mode, PW Doppler analysis and contemporary techniques-TDI and 2D-Speckle-Tracking Echocardiography). We evaluate LV diastolic and systolic function and its correlation with basic clinical characteristics (age, gender, BMI, BSA, waist to hip ratio, duration of diabetes) and biochemical analyses (glucose profile, lipid profile, CRP). The correlation between clinical, biochemical and echocardiographic parameters was assessed by the Pearson Product Moment of Correlation. A p-value of < 0.05 was considered to indicate significance. Results: Analysis of deformation identify the greatest number of subjects with abnormal myocardial mechanics (n=45, 62%). Wilcoxon Matched Pairs Test showed a statistically significant difference between the groups regarding the prevalence of diastolic dysfunction, in each imaging modality-PWD and TDI (Z=2.3, p=0.01; Z=2.9, p=0.003). There were strong negative correlations between clinical, biochemical and echocardiographic parameters of PW Doppler and 2D Speckle-Tracking Echocardiography and strong positive correlation with TDI. Conclusion: Doppler echocardiography is a valuable imaging technique for identifying LV dysfunction in asymptomatic patients with diabetes, and is an important part of the diagnostic algorithm in diabetic cardiomyopathy. Novel Doppler-echocardiographic techniques as are Tissue Doppler Imaging and Speckle-Tracking Echocardiography show superiority over other echocardiographic methods, regarding the early detection of LV functional abnormalities in the asymptomatic diabetic population. Its introduction in daily routine will contribute to the timely initiation of treatment of risk factors, to prevent the development of heart failure

Product Identifiers

Publisher
NOVA Science Publishers INC International Concepts
ISBN-13
9781536169577
eBay Product ID (ePID)
16046696947

Product Key Features

Author
Slavica Mitrovska
Publication Name
Diabetic Cardiomyopathy: Echocardiographic and Clinical Characteristics
Format
Hardcover
Language
English
Subject
Medicine
Publication Year
2020
Type
Textbook
Number of Pages
282 Pages

Dimensions

Item Weight
546g

Additional Product Features

Title_Author
Slavica Mitrovska
Country/Region of Manufacture
United States

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ABC Books Ltd
Unit 2D
Gatwick Gate Industrial Estate
Crawley, Lowfield Heath
London
RH11 0TG
United Kingdom
Btw-nummer:
  • GB 324767388
Handelsregistratienummer:
  • 05034144
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