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Reversible Ligand Binding: Theory and Experiment by Andrea Bellelli: Used
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Specificaties
- Objectstaat
- Book Title
- Reversible Ligand Binding: Theory and Experiment
- Publication Date
- 2017-12-29
- ISBN
- 9781119238485
- Subject Area
- Science
- Publication Name
- Reversible Ligand Binding : Theory and Experiment
- Publisher
- Wiley & Sons, Incorporated, John
- Item Length
- 9.7 in
- Subject
- Life Sciences / Biochemistry
- Publication Year
- 2018
- Type
- Textbook
- Format
- Hardcover
- Language
- English
- Item Height
- 0.7 in
- Item Weight
- 22.4 Oz
- Item Width
- 6.6 in
- Number of Pages
- 304 Pages
Over dit product
Product Identifiers
Publisher
Wiley & Sons, Incorporated, John
ISBN-10
111923848X
ISBN-13
9781119238485
eBay Product ID (ePID)
19038444119
Product Key Features
Number of Pages
304 Pages
Language
English
Publication Name
Reversible Ligand Binding : Theory and Experiment
Publication Year
2018
Subject
Life Sciences / Biochemistry
Type
Textbook
Subject Area
Science
Format
Hardcover
Dimensions
Item Height
0.7 in
Item Weight
22.4 Oz
Item Length
9.7 in
Item Width
6.6 in
Additional Product Features
Intended Audience
Scholarly & Professional
LCCN
2017-026931
Illustrated
Yes
Synopsis
Presents the physical background of ligand binding and instructs on how experiments should be designed and analyzed Reversible Ligand Binding: Theory and Experiment discusses the physical background of protein-ligand interactions--providing a comprehensive view of the various biochemical considerations that govern reversible, as well as irreversible, ligand binding. Special consideration is devoted to enzymology, a field usually treated separately from ligand binding, but actually governed by identical thermodynamic relationships. Attention is given to the design of the experiment, which aids in showing clear evidence of biochemical features that may otherwise escape notice. Classical experiments are reviewed in order to further highlight the importance of the design of the experiment. Overall, the book supplies students with the understanding that is necessary for interpreting ligand binding experiments, formulating plausible reaction schemes, and analyzing the data according to the chosen model(s). Topics covered include: theory of ligand binding to monomeric proteins; practical considerations and commonly encountered problems; oligomeric proteins with multiple binding sites; ligand binding kinetics; hemoglobin and its ligands; single-substrate enzymes and their inhibitors; two-substrate enzymes and their inhibitors; and rapid kinetic methods for studying enzyme reactions. Bridges theory of ligand binding and allostery with experiments Applies historical and physical insight to provide a clear understanding of ligand binding Written by a renowned author with long-standing research and teaching expertise in the area of ligand binding and allostery Based on FEBS Advanced Course lectures on the topic Reversible Ligand Binding: Theory and Experiment is an ideal text reference for students and scientists involved in biophysical chemistry, physical biochemistry, biophysics, molecular biology, protein engineering, drug design, pharmacology, physiology, biotechnology, and bioengineering., Presents the physical background of ligand binding and instructions on designing and analyzing experiments Reversible Ligand Binding: Theory and Experiment discusses the physical background of protein-ligand interactions providing a comprehensive view of the principles that govern reversible, as well as irreversible, ligand binding. Special consideration is devoted to enzymology, a field usually treated separately from ligand binding, but actually governed by identical thermodynamic relationships. Attention is given to the design of experiments, including how to uncover evidence of biochemical features that may otherwise escape notice. Classical experiments are reviewed in order to further highlight the importance of the experimental design. Overall, the book supplies students with understanding necessary for interpreting ligand binding experiments, formulating plausible reaction schemes, and analyzing the data according to a chosen model. Topics covered include: theory of ligand binding to monomeric proteins; practical considerations and commonly encountered problems; oligomeric proteins with multiple binding sites; ligand binding kinetics; hemoglobin and its ligands; single-substrate enzymes and their inhibitors; two-substrate enzymes and their inhibitors; and rapid kinetic methods for studying enzyme reactions. Bridges theory and experiment in ligand binding and allostery Applies historical and physical insight to provide clear understanding of ligand binding Written by renowned authors with long research and teaching expertise in the areas of ligand binding and allostery Reversible Ligand Binding: Theory and Experiment is an ideal text for students and scientists involved in biophysical chemistry, physical biochemistry, biophysics, molecular biology, protein engineering, drug design, pharmacology, physiology, biotechnology, or bioengineering.
LC Classification Number
QP517.L54B45 2017
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