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Dextromethorph
GBP 177,99
OngeveerEUR 213,46
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GBP 15,99 (ongeveer EUR 19,18) Standard Int'l Postage.
Bevindt zich in: Castle Donington, Verenigd Koninkrijk
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Geschatte levering tussen do, 17 okt en di, 29 okt tot 43230
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eBay-objectnummer:196206514945
Specificaties
- Objectstaat
- Book Title
- Dextromethorphan : Pharmacology, Clinical Uses and Health Effects
- ISBN
- 9781634840163
- Publication Year
- 2016
- Type
- Textbook
- Format
- Hardcover
- Language
- English
- Publication Name
- Dextromethorphan: Pharmacology, Clinical Uses & Health Effects
- Item Height
- 260 mm
- Publisher
- NOVA Science Publishers INC International Concepts
- Item Width
- 180 mm
- Subject
- Medicine
- Item Weight
- 538 g
- Number of Pages
- 216 Pages
Over dit product
Product Information
Dextromethorphan (DM) is an over-the-counter antitussive drug that is also used as one of the active ingredients in many cold and cough medicines. In recent years, DM has also been used in other medicines, ranging from pain relief (as either the primary analgesic or an opioid potentiater) over psychological applications to the treatment of addiction. Pharmacodynamics of DM have been gradually discovered with the elucidation of the following properties, including uncompetitive NMDA receptor antagonist, sigma1 and sigma2 sigma receptor agonists, alpha3ss4-nACh receptor antagonist, and others. DM is transformed to its primary and active metabolite dextrorphan predominantly via the metabolic enzyme cytochrome P450 (CYP) 2D6. Hence, DM is the first-choice substrate for CYP2D6 phenotyping because it is relatively safe and possesses many favorable pharmacokinetic characteristics for a marker substrate. This book aims to meet the needs of basic molecular biochemists, pharmacologists, pharmacists, medical students, clinical practitioners and scientists, as well as broad readers who wish to understand the pharmacology of DM and its clinical uses. The contributing authors are basic scientists, pharmacologists, pharmacists and on-service physicians in neuro-psychiatric, anesthesiologic and hepatologic fields from the Czech Republic, Austria, the United States, and China. As a collection of masterpieces by well-known experts, this book presents current research in the study of DM, focusing on its pharmacology, clinical uses and health effects. Topics discussed in this compilation include the new pharmacological application of DM; pharmacogenetics of DM; pharmacodynamics and toxicological profiles of DM; long cutaneous block by lidocaine and DM; toxic and beneficial effects of DM on the central nervous system; pharmacokinetics of DM and drug interactions; DM as a probe drug for CYP2D6 and CYP3A4 phynotyping; evaluation of CYP2D6 in DM-herb interactions; and clinical uses and health effects of DM.
Product Identifiers
Publisher
NOVA Science Publishers INC International Concepts
ISBN-13
9781634840163
eBay Product ID (ePID)
221291797
Product Key Features
Publication Name
Dextromethorphan: Pharmacology, Clinical Uses & Health Effects
Format
Hardcover
Language
English
Subject
Medicine
Publication Year
2016
Type
Textbook
Number of Pages
216 Pages
Dimensions
Item Height
260 mm
Item Width
180 mm
Item Weight
538 g
Additional Product Features
Country/Region of Manufacture
United States
Editor
Dr Xin Wang
Objectbeschrijving van de verkoper
Informatie van zakelijke verkoper
Far Corner Europe Limited
Barbara Blake
19-20 Bourne Court
Southend Road
Woodford Green
Essex
IG8 8HD
United Kingdom
Btw-nummer:
- GB 307932304
Handelsregistratienummer:
- 10691061
Ik verklaar dat al mijn verkoopactiviteiten zullen voldoen aan alle wet- en regelgeving van de EU.
KVK-nummer:
- 10691061
Ingeschreven als zakelijke verkoper
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